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Question

According to which theory of ageing, ageing is the result of the sequential switching on and off of certain genes?

A
Cross linking theory
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B
Endocrine threory
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C
Programmed senescence theory
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D
Somatic mutation theory
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Solution

The correct option is C Programmed senescence theory
Modern biological theories of ageing in humans fall into two main categories: programmed and damage or error theories. The programmed theories imply that ageing follows a biological timetable, a continuation of the one that regulates childhood growth and development. This regulation would depend on changes in gene expression that affect the systems responsible for maintenance, repair and defence responses. The programmed theory has three sub-categories: programmed longevity - ageing is the result of a sequential switching on and off of certain genes, with senescence being defined as the time when age-associated deficits are manifested.

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