Question

Acetyl CoA is synthesized in the

• A. Cytosol
• B. Inner membrane of mitochondria
• C. Matrix of mitochondria
• D. $F_1$ particles of mitochondria

Answer 1

The correct option is C Matrix of mitochondria

Pyruvic acid is the product of glycolysis that takes place in the cytosol. Pyruvate dehydrogenase complex is a cluster of three enzymes and is present in multiple copies in the matrix mitochondria of eukaryotic cells. It catalyzes irreversible oxidative decarboxylation of pyruvate into acetyl-CoA and carbon dioxide. Inner mitochondrial membrane carries electron transport chain. $F_1$ particles of mitochondria catalyze the synthesis of ATP using the protonmotive force. Thus, the correct answer is option C.