Acidic amino acids carry two - COOH and one - NH2 groups per molecule. With respect to this, select the correct pair of acidic amino acid.
A
Lysine and arginine
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B
Aspartic acid and glutamic acid
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C
Glycine and alanine
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D
Both A and B
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Solution
The correct option is D Both A and B Two amino acids have acidic side chains at neutral pH. These are aspartic acid or aspartate and glutamic acid or glutamate. Their side chains have carboxylic acid groups whose pKa's are low enough to lose protons, becoming negatively charged in the process.