The correct option is D STH
Acromegaly is a syndrome, that results when the anterior pituitary gland produces excess growth hormone (GH) or somatotropin (STH) after epiphyseal plate closure at puberty. Acromegaly most commonly affects adults in middle age. Enlargement of the hands and feet is one of the most common signs of the disease. Other effects include enlargement of the jaw and other facial bones; overgrowth of bone and cartilage in the joints, curvature of the spine (kyphosis), swelling of the face, lips, and tongue; breathing problems during sleep (sleep apnea); thickening of the skin; carpal tunnel and other nerve entrapment syndromes. Thus, the correct answer is D.