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Question

Active sites of actin are blocked by

A
Troponin
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B
Tropomyosin
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C
Myosin
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D
Actinomyosin
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Solution

The correct option is C Tropomyosin
Tropomyosin blocks myosin binding sites on actin molecules, preventing cross-bridge formation and preventing contraction in a muscle without nervous input. Tropomyosin is removed from the actin binding site when calcium ions bind to troponin, causing conformational changes in troponin that allow tropomyosin to move away from the myosin binding sites on actin.
So, the correct answer is 'Tropomyosin'.

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