Question

ADA- Adenosine deaminase enzyme does not function. It occurs as a result of

• A. Hormonal defect
• B. Genetic defect
• C. Metabolic defect
• D. Both B and C

Answer 1

Answer: (D)

Both B and C

• Adenosine deaminase enzyme converts deoxyadenosine (a toxic substance) to another molecule called deoxyinosine (not harmful).
  
• Mutations cause this enzyme to become unstable and prevents it from being produced.
  
• It also causes the deficiency of the adenosine deaminase enzyme in cells and prevents the normal breakdown of deoxyadenosine.
  
• So, the correct answer is 'Both B and C'.