Advantages of selecting drosophila as an experimental organisms in genetics
Advantages of selecting drosophila as an experimental organisms in genetics
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Drosophila melanogaster is a small, easily reared insect with a short lifecycle.
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The key advantages of Drosophila are a balance between genetic power and biomedical relevance, and rapidity and low cost of generation and maintenance of mutant and transgenic stocks.
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The genetic toolbox available for Drosophila allows precise intervention in specific, defined cells in an otherwise normal organism, opening unique opportunities for functional biology.
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Approximately 70% of human genes have clear Drosophilahomologues, allowing the modelling of many human diseases in flies.
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Drosophila also shares approximately 70% of its genes with Anopheles gambiae, the mosquito vector of malaria.
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Our understanding of fly development is now mature: new phenotypes are required to provide a global functional genomic understanding.
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An exciting challenge for the future is functional biology; understanding how the different tissues and control systems interact to make a working, successful organism.
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Drosophila melanogaster is a small, easily reared insect with a short lifecycle.
-
The key advantages of Drosophila are a balance between genetic power and biomedical relevance, and rapidity and low cost of generation and maintenance of mutant and transgenic stocks.
-
The genetic toolbox available for Drosophila allows precise intervention in specific, defined cells in an otherwise normal organism, opening unique opportunities for functional biology.
-
Approximately 70% of human genes have clear Drosophilahomologues, allowing the modelling of many human diseases in flies.
-
Drosophila also shares approximately 70% of its genes with Anopheles gambiae, the mosquito vector of malaria.
-
Our understanding of fly development is now mature: new phenotypes are required to provide a global functional genomic understanding.
-
An exciting challenge for the future is functional biology; understanding how the different tissues and control systems interact to make a working, successful organism.
