Albinism is an inherited condition caused by a recessive allele a. A is the dominant allele for the normal condition. What are the genotypes of individuals R and S?
A
R = AA, S=AA
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B
R = AA, S=Aa
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C
R = Aa, S=Aa
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D
R = aa, S=aa
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Solution
The correct option is B R = Aa, S=Aa
In generation 1, the albino male and albino female will have their genotype as "aa" (recessive allele for albinism).
In an autosomal recessive pedigree, normal male and female may have their genotype as "AA" or "Aa".
All children in generation 2 are normal. Hence, their genotypes will be "Aa" because one of their parent is affected and can only transfer recessive allele to their children.
In generation 3, there are 7 children (2 normal males, 3 normal females, 1 albino male, and 1 albino female).
The genotypes of normal children will be "Aa", whereas that of albino children will be "aa". R and S belong to generation 2, where all the children are normal with their genotype as "Aa".