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Question
Albinism is known to occur due to an autosomal recessive mutation. The first child of a couple with normal skin pigmentation was an albino. What is the probability that their second child will also be an albino?
Albinism is known to occur due to an autosomal recessive mutation. The first child of a couple with normal skin pigmentation was an albino. What is the probability that their second child will also be an albino?
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Solution
The correct option is D 25%
Since, the couple has normal pigmentation but their first child has albinism, thus, the genotype of the couple is A Aa (where A is the autosome and Aa is the autosome carrying gene for albinism)P generation: A Aa X A AaF1 generation: AA AAa AAa AaAa (Normal) (Albino)Normal : Albino = 3 : 1
Since, the couple has normal pigmentation but their first child has albinism, thus, the genotype of the couple is A Aa (where A is the autosome and Aa is the autosome carrying gene for albinism)
P generation: A Aa X A Aa
F1 generation: AA AAa AAa AaAa
(Normal) (Albino)
Normal : Albino = 3 : 1
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