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Question

All enzymes of TCA cycle are located in the mitochondrial matrix except one, which is located in the inner mitochondrial membranes in eukaryotes and cytosol in prokaryotes. This enzyme is ______.

A
Lactate dehyrogenase
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B
Isocitrate dehydrogenase
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C
Malate dehydrogenase
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D
Succinate dehydrogenase
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Solution

The correct option is D Succinate dehydrogenase

Succinate dehydrogenase enzyme is present on inner membrane of mitochondria and is a part of the complex II in the ETC. It catalyses the oxidation of succinate to fumarate in the Kreb's cycle and channels the FADH2 produced during this reaction into the ETC.


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