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Question

All mutations in genetic material may not lead to change in amino acid composition. Though there is a change in the codon, it is not expressed in the amino acids. Such mutations are called as silent mutations'. Which of the following alteration of codons ATTGCC is not a silent mutation?

A
ATCGCC
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B
ATTGCA
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C
ATTTGC
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D
ATCGCG
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Solution

The correct option is C ATTTGC
The mutation which results in the change in the nucleotide but the amino acid in the protein is same is known as silent mutation. The sequences which are given in the options A, B and D are showing the difference in the third nucleotide of the codon which will code for the same or similar amino acid. The sequence given in the option C is showing the first nucleotide to be changed which will change the amino acid coded in the protein.
Thus, the correct answer will be option C.

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