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Question

Amino acid binding site of tRNA has

A
CCA - OH
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B
CGA - OH
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C
UCA - OH
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D
UCG - OH
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Solution

The correct option is A CCA - OH
Transfer ribonucleic acid or tRNA is a type of RNA molecule that serves as an adaptor in translating the language of nucleic acids into the language of proteins. They are relatively small and consist of a single strand of RNA folded into a precise three-dimensional structure (the cloverleaf secondary structure). Most tRNAs have a guanylate (pG) residue at the 5' end and all have the trinucleotide sequence CCA (3') at the 3' end. The CCA tail of the amino acid arm is a cytosine-cytosine-adenine sequence at the 3' end of the tRNA molecule. The amino acid loaded onto the tRNA by aminoacyl tRNA synthetases, to form aminoacyl-tRNA, is covalently bonded to the 3'-hydroxyl group on the CCA tail. This sequence is important for the recognition of tRNA by enzymes and critical in translation. Therefore, option A is correct answer.
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