Among the given compounds, the most susceptible to nucleophilic attack at the carbonyl group is:

C H_{3} C O C l

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C H_{3} C H O

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C H_{3} C O O C H_{3}

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C H_{3} C O O C O C H_{3}

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Solution

The correct option is A $C H_{3} C O C l$
The most susceptible to nucleophilic attack at the carbonyl group is acetyl chloride $(C H_{3} C O C l)$ . In general, acid chlorides are most susceptible to nucleophilic attack at the carbonyl group as chloride ion is a very good leaving group.

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The most characteristic reaction of aldehyde and ketones is nucleophilic addition to carbon oxygen double bond. Aldehyde and ketones are easily susceptible to nucleophilic addition because of structural features. The trigonal planar arrangement of groups around the carbonyl carbon atom means that the carbonyl carbon atom is relatively open to attack from above and below the plane of carbonyl group. The partial positive charge on the carbonyl atom means that it is especially susceptible to attack by a nucleophile

Aldehyde reacts with $2^{\circ}$ amines to form

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Among the given compounds, the most susceptible to nucleophilic attack at the carbonyl group is:

The correct option is A CH3COClThe most susceptible to nucleophilic attack at the carbonyl group is acetyl chloride (CH3COCl). In general, acid chlorides are most susceptible to nucleophilic attack at the carbonyl group as chloride ion is a very good leaving group.

The correct option is A $C H_{3} C O C l$
The most susceptible to nucleophilic attack at the carbonyl group is acetyl chloride $(C H_{3} C O C l)$ . In general, acid chlorides are most susceptible to nucleophilic attack at the carbonyl group as chloride ion is a very good leaving group.