Question

Among these, Tay-Sachs disease is due to

• A. Hexosaminidase A protein deficiency in children leading to damaging affects on the muscle growth and development in children.
• B. An inherited disorder in which the spinal cord and brain are severely damaged within a few months of birth leading to paralysis.
• C. Both A and B.
• D. None of the above.

Answer 1

The correct option is C Both A and B.

Tay-Sachs disease is a rare inherited disorder that progressively destroys nerve cells in the brain and the spinal cord. The most common form of Tay-Sachs disease becomes apparent in infancy. Infants with this disorder typically appear normal until the age of 3-6 months, when their development slows down and muscles used for movement weaken. As the disease progresses, children with Tay-Sachs experience seizures, vision and hearing loss, intellectual disability and paralysis.

Thus, the correct answer is option C.