Question

Amongst the following compounds, the one which would not respond to iodoform test is:

• A. $C{H}_{3}CH\left(OH\right)C{H}_{2}C{H}_3$
• B. $IC{H}_{2}COC{H}_{2}C{H}_3$
• C. $C{H}_{3}COOH$
• D. $C{H}_{3}CHO$

Answer 1

The correct option is C $C{H}_{3}COOH$

Acetic acid, $C{H}_{3}COOH$ would not respond to iodoform test. In the mechanism of haloform reaction, in the first step, base deprotonates most acidic alpha H atom (of methyl keto group).
In acetic acid, the most acidic proton is attached to O atom. So deprotonation of $\alpha$−hydrogen does not occur and hence no haloform reaction.