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Question

Amount of oxygen supplied by 100 ml arterial blood, while passing through the tissues is

A
0.4 - 0.6 ml
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B
4 - 6 ml
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C
14 - 15 ml
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D
19 - 20 ml
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Solution

The correct option is C 4 - 6 ml
The total quantity of oxygen carried by 100 ml of blood is sum total of oxygen contained in RBC and oxygen dissolved in blood plasma. Since 1 gm of fully oxygenated Hb contains 1.39 ml of oxygen at 100 mm of Hg pressure and average haemoglobin level of adult human is 15 gm/100ml blood. Therefore, total oxygen content of 100mL of arterial blood at 100 mm Hg pressure is 1.39 x Hb x % of saturation +0.003 x partial pressure of oxygen = 1.39 x 15 x 1 +0.003 x 100=21.15 ml/100 ml.
Since the partial pressure of oxygen in venous blood is 40 mm Hg and haemoglobin is 75% saturated. So, the oxygen content of 100 ml of venous blood at 100 mm Hg pressure = 1.39 x 15 x 0.75 +0.003 x 40 = 15.75 ml/100 ml. This means that at tissue level, 21.15-15.75 = 5.4 ml of oxygen is being extracted, which makes option B correct answer.

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