The correct option is
D Both B and C
The proteins are made up of amino acids. The amino acids have 4 groups attached to the central carbon atom; carboxyl group at one end and amine group at the other end, a hydrogen and a side chain (R). Glutamate and aspartate has acidic side chains at neutral pH. They have carboxyl group at the end which has low acid dissociation value and can easily lose proton thus they are acidic in nature
So, the correct answer is option D.