Question

An administration of estrogen and progesterone to the woman decreases the secretion of gonadotropins due to

• A. Positive feedback inhibition
• B. Negative feedback inhibition
• C. Chemical reaction between the hormones
• D. None of the above

Answer 1

The correct option is B Negative feedback inhibition

• A feedback mechanism for multistep reactions is a biological occurrence wherein the output of a system amplifies the system (positive feedback) or inhibits the system (negative feedback).
• For example, Release of estrogen from the ovaries stimulates the secretion of GnRH from Hypothalamus which in turn stimulates the secretion of LH from anterior pituitary.when the levels of LH reaches above the normal levels in the blood it stimulates the release of progesterone from corpus luteum which causes the inhibition of the release of GnRH from the hypothalamus which in turn leads to inhibition of release of LH(product) from anterior pituitary and prevents the accumulation of LH(product)in blood. Hence negative feedback.
• Hence An administration of estrogen and progesterone to the woman decreases the secretion of gonadotropins due to Negative feedback inhibition.
• So, the correct answer is 'Negative feedback inhibition'.