An anticoagulant used for preventing clotting in vitro is sodium oxalate. It prevents clot formation by
A
Combining with cations in the blood
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B
Inhibiting clotting factor VIII activity
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C
Getting itself deposited over the surface of RBC
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D
Blocking the fibrinogen activity
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Solution
The correct option is B Combining with cations in the blood
Sodium oxalate (like citrates) can be used to remove calcium ions (Ca2+$2+) from the blood plasma. The oxalate prevents clotting by forming insoluble calcium salts, thus removing ionic calcium (or cations). Therefore, the correct answer is option A.