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Question

An enzyme which joins small pieces of DNA, is:

A
RNA ligase
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B
ATP ligase
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C
AMP ligase
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D
DNA ligase
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Solution

The correct option is B DNA ligase
An enzyme that joins small pieces of DNA is DNA ligase. DNA ligase is a specific type of enzyme, a ligase that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bonds. It plays a role in repairing single-strand breaks in duplex DNA in living organisms, but some forms (such as DNA ligase IV) may specifically repair double-strand breaks (a break in both complementary strands of DNA). Single-strand breaks are repaired by DNA ligase using the complementary strand of the double helix as a template, with DNA ligase creating the final phosphodiester bond to fully repair the DNA.

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