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Question

An example of feedback inhibition is


A

cyanide action on cytochrome

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B

sulpha drug on folic acid synthesiser bacteria

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C

allosteric inhibition of hexokinase by glucose 6-phosphate

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D

reaction between succinic dehydrogenase and succinate

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E

the inhibition of succinic dehydrogenase by malonate

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Solution

The correct option is C

allosteric inhibition of hexokinase by glucose 6-phosphate


In feedback inhibition, the product of an enzyme-catalysed reaction (chain of reactions) accumulates and acts as an inhibitor of the reaction, e.g.
Glucose+ATPHexokinase−−−−−−Glucose6phosphate+ADP


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