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Question

An increase in P50 of an oxyhaemoglobin curve would result from a decrease in.

A
Oxygen
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B
pH
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C
Metabolism
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D
Temperature
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Solution

The correct option is A pH

The P50 represents the partial pressure at which hemoglobin is 50 percent saturated with oxygen.

Normal P50 is 27 mm Hg

P50 provides a means of quantifying the hemoglobin's affinity (willingness to bond) with oxygen. Reflects what are called shifts of the dissociation curve.

When there is a decrease in pH ( acidic environment) , the oxygen dissociation curve shifts towards Right – hemoglobin has decreased affinity, increased P50 – takes more oxygen to reach 50% (higher partial pressure to get 50% saturated)

So, the correct answer is 'pH'


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