An increase in P50 of an oxyhaemoglobin curve would result from a decrease in.
The P50 represents the partial pressure at which hemoglobin is 50 percent saturated with oxygen.
Normal P50 is 27 mm Hg
P50 provides a means of quantifying the hemoglobin's affinity (willingness to bond) with oxygen. Reflects what are called shifts of the dissociation curve.
When there is a decrease in pH ( acidic environment) , the oxygen dissociation curve shifts towards Right – hemoglobin has decreased affinity, increased P50 – takes more oxygen to reach 50% (higher partial pressure to get 50% saturated)
So, the correct answer is 'pH'