An isolated population of humans with equal number of blue-eyed and brown-eyed individuals was decimated by an earthquake. Only a few brown-eyed remained to form the next generation. This kind of change in the gene pool is called
Bottle neck effect
Natural calamities like earthquake reduce the size of a population. The brown-eyed individuals formed the next generation though the genetic pool of the small surviving population is not a representative of genetic pool of the original population which is called as bottle neck effect.