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Question

An SN2 reaction at an asymmetric carbon of a compound always gives:

A
A mixture of diastereomers
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B
A single stereoisomer
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C
A product with opposite optical rotation
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D
An enantiomer of the substrate
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Solution

The correct option is B A single stereoisomer
SN2 reaction at asymmetric carbon occurs with inversion of configuration and a single stereoisomer is formed because the reactants and products are not enantiomers. Therefore the sign of optical rotation may or may not change.

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