An unsubstituted amide,is converted into the acid and nitrogen by:
The Conversion of an amide by action of NaOH and Br2 to primary amine that has one carbon less than the starting amide is known as Hofmann-Bromamide reaction.
R−O||C−NH2Br2+NaOH−−−−−−−→(or)NaoBr R−NH2+NaBr+Na2CO3
Conversion of Ketoximes to N- substituted amides is known as Beckmann rearrangement. In this rearrangement migration takes place from carbon to nitrogen. The reaction is catalyzed by acidic reagents. The main function of the acidic catalyst is to convert -OH of the oxime into a better leaving group by protonation.