Question

Anaesthetics reduce pain by blocking nerve conduction due to

• A. Blocking neurotransmitter receptors
• B. Blocking N$a^{+}$ channels
• C. Blocking $K^{+}$ channels
• D. All the above

Answer 1

The correct option is B Blocking N$a^{+}$ channels

B. Bloking Na+ channels

Reason: Anesthetic molecules interact with the sodium channels directly, from the inner side of the nerve membrane. It binds within sodium channels that have opened during membrane depolarization, preventing the normal sodium ion flux. Thus, it prevents the action potential and conduction of signals. So the correct option is A.