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Question

Angiotensinogen is a protein produced and secreted by ________________.

A
Juxtaglomerular (JG) cells
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B
Macula densa cells
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C
Endothelial cells (cells lining the blood vessels)
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D
Liver cells
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Solution

The correct option is D Liver cells
Angiotensinogen is a αα - globulin protein produced by liver cells. Renin changes angiotensinogen to angiotensin II (hormone) in response to fall in glomerular blood flow/glomerular blood pressure/GFR. Angiotensin II increases blood pressure and blood volume.

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