The correct options are
A They interfere with the bacterial DNA repair system and thus prevent it from reproduction
B Antibiotics do not allow the bacteria to build cell wall.
D They weaken the bacterial cell wall and make it rupture.
Antibiotics affect the pathogen by different mechanisms.
1. Some of them interfere with the DNA repair mechanism of the bacteria. Unless DNA is repaired, the bacterial cell cannot reproduce.
2. Some of the antibiotics make the bacterial cell wall weak. With the weak cell wall, the bacterial cells lyse (burst), thus reducing it's population.
3. Few antibiotics do not allow the bacteria to build cell wall.