Question

Antigen antibody reactions are suppressed in

• A. Liver dysfunction
• B. Chronic inflammatory reactions
• C. ACTH excess
• D. Vit – K excess

Answer 1

The correct option is C

ACTH excess

ACTH (adreno cortico trophic hormone) stimulates the adrenal cortex to produce its hormones. Cortisone is a hormone of adrenal cortex which has a suppressing effect on the immune system. So, excess ACTH will lead to excess production of cortisone which inturn leads to suppression of immune response.