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Standard XII
Biology
Biotechnology
Are Prions Se...
Question
Are prions self-replicating?
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Solution
Prions:
They are
proteinaceous infectious particles.
They cause several neurodegenerative diseases in mammals, eg-Creutzfeldt Jakob disease.
They are self-replicating misfolded proteins.
They pass on their conformation to other proteins which leads to aggregation in pathogens.
When these pathogens enter a healthy individual, prions induce the properly-folded proteins to alter into prion forms that are linked to diseases.
They use the non-essential genes present in the host for synthesizing misfolded proteins.
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