Question

Arrange the following step in correct sequence found during the mechanism of lipid insoluble hormone (epinephrine) function or action.

A. Second messenger formation

B. Binding to the surface receptor

C. Glycogenolysis

D. Adenylate cyclase activation

• A. C, A, D and B
• B. B, D, A and C
• C. D, B, C and A
• D. None of the above

Answer 1

The correct option is B B, D, A and C

Lipid insoluble hormones such as epinephrine acts or functions on a particular site by binding to it. These hormones have their receptors on the plasma membrane of the target cells. The binding of hormone to the receptor initiates a series of events. These series of events are called as signal transduction. In this, the hormone first binds to the surface receptor. It leads to the activation of the enzyme adenylate cyclase. This enzyme converts the ATP into cyclic AMP or cAMP inside the cell. This cAMP acts as second messenger. This cAMP then activates cAMP-dependent protein kinase called protein kinase A. This proteni kinase A triggers a series of molecular interactions that leads to glycogenolysis. This results in the synthesize of glucose from glycogen.

Thus, the correct answer is 'B, D, A and C.'