The correct option is C SQPR
The orders of words should be Subject+ verb+ subordinate clause (S)+ subordinating conjunction(Q)+ adverbial clause(P)+ alternative predicate( R). Hence, Option C, that is, "All the evil in this world is brought about by persons who are always up and doing but do not know when they ought to be up nor what they ought to be doing." is correct. The rest of the options do not adhere to this rule, hence incorrect.