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Chromosomes

As DNA is neg...

Question

As DNA is negatively charged (or acidic) and histone are positively charged in their side chain(or basic).. Can we assume that nucleosome as a whole will be neutral neither acidic nor basic

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Solution

Yes.it is nuetral as a whole.

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Q. Go through the following statements
(i) A typical nucleosome contains 400 bp of DNA helix.
(ii) The positively charged DNA is wrapped around the negatively charged histone octamer to form a structure called nucleosome.
(iii) Histones are rich in the basic amino acid residues asparagine and valine
(iv) The packing of chromatin at higher level requires additional set of proteins that collectively are referred to as Non-histone chromosomal proteins.

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