Aspergillus niger is used in the manufacture of citric acid and gluconic acid. A. niger is cultured for the industrial production of many substances. Many useful enzymes are produced using industrial fermentation of A. niger. For example, glucoamylase of A. niger is used in the production of high fructose corn syrup, and pectinases are used in cider and wine clarification. α-galactosidase, an enzyme that breaks down certain complex sugars, is a component of Beano and other products that decrease flatulence. Another use for A. niger within the biotechnology industry is in the production of magnetic isotope-containing variants of biological macromolecules for NMR analysis. Thus, the correct answer is option A.