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Question

Assertion :A bacterial cell with no restriction enzymes will be easily infected and lysed by bacteriophages. Reason: Restriction enzymes catalyse synthesis of protective coat around bacterial cell that prevents bacteriophage attack.

A
Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
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B
Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
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C
Assertion is correct but Reason is incorrect
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D
Both Assertion and Reason are incorrect
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Solution

The correct option is C Assertion is correct but Reason is incorrect
Restriction enzymes were named due to the phenomenon of host restriction of bacterial phages. Restriction enzymes produced in a bacterial cell, recognise and cleave foreign DNA introduced (such as from bacteriophage) into the cell. Thus, bacterial cell cannot be infected and lysed by bacteriophage and hence a bacterial cell lacking restriction enzymes is easily susceptible to infection of phages. The DNA of the host bacterial cell is protected from its own restriction endonucleases by methylation (usually of A and C) within their recognition sites.
So, the correct answer is 'Assertion is correct but Reason is incorrect'.

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