Question

Assertion :A blood sugar level falls rapidly after hepatectomy. Reason: The glycogen of the liver is the principle source of blood sugar.

• A. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
• B. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
• C. Assertion is correct but Reason is incorrect
• D. Both Assertion and Reason are incorrect

Answer 1

The correct option is A Both Assertion and Reason are correct and Reason is the correct explanation for Assertion

The liver is the principal organ in the regulation of the blood sugar level. Liver cells play a key role in regulating the blood glucose level as they can either break down glycogen (glycogenolysis) to release glucose into the blood or withdraw glucose from the blood and store it by synthesizing glycogen (glycogenesis). If the liver is removed there is a progressive hypoglycemia which ends in death. After hepatectomy it is not possible to provoke hyperglycemia, whatever the agent or procedure employed, whether the animal were diabetic or not before the liver was removed. Nor is it possible to produce any form of diabetes in hepatectomized animals. On the other hand, when there is hyperglycemia the liver diminishes or ceases the production of sugar and stores it.