Question

Assertion [A]: Patients suffering from Klinefelter's syndrome have high amounts of estrogen secreted in their body.

Reason [R]: Klinefelter's syndrome occurs due to the presence of an extra X chromosome in human males.

• A. A is True and R is False
• B. R is True and A is False
• C. Both A and R are true and R is a correct explanation for A
• D. Both A and R are true but R is not a correct explanation to A

Answer 1

The correct option is C Both A and R are true and R is a correct explanation for A

Klinefelter's syndrome is a genetic disorder in which males have one extra X chromosome. Hence, their chromosomal condition becomes 44+XXY. This additional X chromosome leads to severe hormonal imbalance. The patient would have lesser amount of testosterone in the body and higher production of estrogen. This results in sterility and poor development of male secondary sexual characters.