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Question

Assertion: A person using cocaine feels high energy level
Reason: Cocaine binds to the neurotransmitter dopamine causing repeated stimulation

A
Both assertion and reason are correct and reason is the correct explanation of the assertion
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B
Both assertion and reason are correct but reason is not the correct explanation of assertion
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C
The assertion is correct but the reason is incorrect
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D
Both assertion and reason are incorrect
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Solution

The correct option is C The assertion is correct but the reason is incorrect
Cocaine is a chemical substance extracted from the plant Erythroxylum coca, it has a stimulatory effect on the nervous system by interfering with the neurotransmitter dopamine.

Neurotransmitters are chemical substances that are responsible for the transmission of impulse (signal) from one neuron to another. Any interference in their action will directly affect the role it plays in the body. Hence on using cocaine an individual does feel high levels of energy, making the assertion a correct statement.

However, the cocaine does not bind to neurotransmitter dopamine. Dopamine is produced in the brain and along with its receptors plays a significant role in movement regulation and has a prominent effect on emotions. The action of dopamine in the body is as follows:

During the transmission of impulse (signal) between two adjacent neurons, dopamine is released in the space or cleft between them. This space is called the synaptic cleft.
On the release of dopamine from one neuron it binds to its specific receptors on the second neuron and thus successfully transmitting the signal between the two neurons. It has been observed that the individual when happy often shows increased levels of dopamine.

However, dopamine is collected by a protein called transporter, clearing them out from the synapse. Once dopamine is taken back by the transporter, the feel-good sensation settles down.


Cocaine blocks this transporter and interferes with the uptake of dopamine from the synapse. This leads to the continuous binding of dopamine to its receptors and thus amplifying the effect of dopamine.



Hence, the reason is not a correct statement.

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