Question

Assertion: Angiotensin II increases GFR
Reason : It is a powerful vasconstrictor

• A. Both the assertion and reason are true and the reason is the correct explanation for the assertion
• B. Both the assertion and reason are true but the reason is not the correct explanation for the assertion
• C. Assertion is true but the reason is false
• D. Reason is true but the assertion is false

Answer 1

The correct option is A Both the assertion and reason are true and the reason is the correct explanation for the assertion

The JGA plays a regulatory role. A fall in glomerular blood flow/glomerular blood pressure/GFR activates the JG cells to release renin which converts angiotensinogen in blood to angiotensin I and further to angiotensin II. Angiotensin II, being a powerful vasoconstrictor, increases the glomerular blood pressure and thereby GFR.