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Question

Assertion :Downstream processing is generally considered more difficult and costlier in plants than that in microbes. Reason: Rhizosecretion is used as a method to facilitate easier recovery of recombinant proteins from plants.

A
Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
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B
Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
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C
Assertion is correct but Reason is incorrect
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D
Both Assertion and Reason are incorrect
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Solution

The correct option is B Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
Purification of desired biochemical from the biomass or the culture medium is called downstream processing. It is generally more difficult and costlier in plants mainly due to low concentration of recombinant protein in the total biomass. Rhizosecretion is one of the methods that overcome this problem. In this method the trans gene is driven by a root specific promoter and an appropriate signal sequence is added to it to ensure the secretion of recombinant protein from the root. Hence, the recombination product is recovered very easily.
So, the correct answer is 'Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion'.

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