Assertion :Genetic engineering requires both nucleases and ligases. Reason: Ligases produce the nick in the recombinant, DNA molecule.

Both Assertion and Reason are correct and Reason is the correct explanation for Assertion

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Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion

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Assertion is correct but Reason is incorrect

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Both Assertion and Reason are incorrect

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Solution

The correct option is C Assertion is correct but Reason is incorrect
Nucleases are the enzymes that remove nucleotides or produce nick in the DNA strand. Exonucleases remove nucleotides from the free ends of DNA while endonucleases produce internal nicks in DNA. Now, the desired gene is inserted and then the cut ends are sealed with the help of DNA ligases. Ligases are also called molecular glue as they join together two DNA strands by forming phosphodiester bonds between adjacent nucleotides.
So, the correct answer is 'Assertion is correct but Reason is incorrect'.

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