Question

Assertion :Hormone calcitonin has antagonistic effect to that of parathormone. Reason: Calcitonin decreases blood calcium level, while parathormone increases blood calcium level.

• A. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion.
• B. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion.
• C. Assertion is correct but Reason is incorrect.
• D. Both Assertion and Reason are incorrect.

Answer 1

The correct option is A Both Assertion and Reason are correct and Reason is the correct explanation for Assertion.

Hormone calcitonin has the antagonistic effect to that of parathormone Calcitonin or thyrocalcitonin is secreted by parafollicular cells of thyroid stroma. It retards bone dissolution and stimulates excretion of calcium in the urine. Thus, It lowers calcium level in extracellular fluid (ECF).

Parathormone is secreted by chief cells of the parathyroid gland and is also known as Collin's hormone. It maintains blood calcium level by increasing its absorption from food in the intestine and its reabsorption from nephrons in the kidney. Maintenance of proper calcium level is in fact, a combined function of parathormone and calcitonin. When calcium level falls below normal, parathormone maintains it by promoting its absorption, reabsorption and also by demineralization of bones. When blood calcium level exceeds above normal then calcitonin hormone increases excretion of calcium in the urine. Hence, option A is correct.