1
Question
Assertion :In Hoffmann bromide reaction, the amine formed has one carbon atom less than the parent 1o amide. Because Reason: N−methyl acetamide undergoes Hoffmann bromamide reaction.
Assertion :In Hoffmann bromide reaction, the amine formed has one carbon atom less than the parent 1o amide. Because Reason: N−methyl acetamide undergoes Hoffmann bromamide reaction.
Open in App
Solution
The correct option is C Assertion is correct but Reason is incorrect
The Hofmann rearrangement is the organic reaction of a primary amide to a primary amine with one fewer carbon atoms.The reaction of bromine with sodium hydroxide forms sodium hypobromite in situ, which transforms the primary amide into an intermediate isocyanate via a formation of a nitrene. The intermediate isocyanate is hydrolyzed to a primary amine, giving off carbon dioxide.
The Hofmann rearrangement is the organic reaction of a primary amide to a primary amine with one fewer carbon atoms.The reaction of bromine with sodium hydroxide forms sodium hypobromite in situ, which transforms the primary amide into an intermediate isocyanate via a formation of a nitrene. The intermediate isocyanate is hydrolyzed to a primary amine, giving off carbon dioxide.
Suggest Corrections
0
Similar questions