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Question

Assertion :Insulin stimulates glycogenolysis and gluconeogenesis resulting in hyperglycemia. Reason: Prolonged hyperglycemia leads to complex disorder called diabetes insipidus.

A
Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
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B
Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
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C
Assertion is correct but Reason is incorrect
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D
Both Assertion and Reason are incorrect
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Solution

The correct option is D Both Assertion and Reason are incorrect
Insulin stimulates conversion of glucose to glycogen (glycogenesis) in the target cells. Whereas, glucagon is a hyperglycemic hormone. Glucagon acts mainly on the liver cells(hepatocytes) and stimulates glycogenolysis resulting in an increased blood sugar (hyperglycemia). In addition, this hormone simulates the process of glucogenesis which also contributes to hyperglycemia. Prolonged hyperglycemia leads to a complex disorder called diabetes mellitus.
So, the correct answer is 'Both Assertion and Reason are incorrect'.

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