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Question

Assertion :JGA is formed by cellular modification in DCT and afferent arteriole at the location of their contact. Reason: Increased GFR activates the JGA to release renin.

A
Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
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B
Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
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C
Assertion is correct but Reason is incorrect
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D
Both Assertion and Reason are incorrect
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Solution

The correct option is C Assertion is correct but Reason is incorrect
The correct answer is option C.
Juxtaglomerular apparatus is formed by the modification in DCT and afferent arteriole at the location of their contact .
JGA consists of Juxtaglomerular cells + macula dens + Mesangial cells.
When the blood volume decreases, blood pressure decreases resulting in the lowering of GFR. Fall in the GFR can activate the JG cells to release renin which can stimulate the glomerular blood flow and there by GFR back to normal.

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