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Question

Assertion :Oxyhaemoglobin dissociates near the organ tissue due to Bohr effect and oxygen is released. Reason: Increased CO2 concentration reduces the affinity of haemoglobin for oxygen.

A
Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
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B
Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
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C
Assertion is correct but Reason is incorrect
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D
Both Assertion and Reason are incorrect
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Solution

The correct option is A Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
  • At lungs where the partial pressure is high, O2 binds with the haemoglobin (purplish-bluish red) in a reversible manner to form oxyhaemoglobin(bright red).
  • At the tissue where the partial pressure of the O2 is low, oxyhaemoglobin dissociates into haemoglobin and oxygen.
  • The other factors that influence the binding of oxygen with haemoglobin are the partial pressure of CO2, the hydrogen ion concentration (pH) and the temperature.
  • The effect of pCO2 and H+ concentration on the O2 affinity of haemoglobin is called as Bohr effect (the increase of CO2 in the blood and decrease in pH results in the reduction of the affinity of haemoglobin for oxygen. Hence, Oxyhaemoglobin dissociates near the organ tissue due to Bohr effect and oxygen is released. due to increased CO2 concentration reduces the affinity of haemoglobin for oxygen.
So, the correct answer is 'Both Assertion and Reason are correct and Reason is the correct explanation for Assertion'.

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