Assertion: Penicillin (G) is an antihistamine.
Reason: Penicillin (G) is effective against gram positive as well as gram negative bacteria.
Both assertion and reason are wrong statements
Assertion
Penicillin (G) is not an antihistamine. It is rather an antibiotic. It is produced by a microorganism (Penicillium, which is a fungus) and it can destroy other microorganisms or can inhibit their growth (even in low concentration) by interrupting their metabolic process.
Hence, it cannot inhibit the production of histamines (a chemical substance that causes allergic reactions in our body) like antihistamines.
So, assertion is wrong statement.
Reason
Penicillin (G) is only effective against gram-positive bacteria and not gram-negative bacteria as it has a narrow spectrum (range of its action is limited to only gram-positive bacteria that is why its spectrum is said to be narrow, not broad).
So, reason is wrong statement.
Hence, both assertion and reason are wrong statements.