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Question

Assertion :Phenylpyruvic acid is excreted through urine in case of phenylketonuria. Reason: The affected individual lacks enzyme phenylalanine hydroxylase.

A
Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
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B
Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
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C
Assertion is correct but Reason is incorrect
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D
Both Assertion and Reason are incorrect
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Solution

The correct option is A Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
Phenylketonuria is an inherited error of metabolism caused by a deficiency in the enzyme phenylalanine hydroxylase. It is an autosomal recessive trait. It is a hereditary human condition resulting from the inability to convert phenylalanine into tyrosine. This leads to over production of phenylalanine and its conversion to phenylpyruvic acid and other derivatives. These are then excreted in urine due to poor absorption by kidneys.
So, the correct answer is 'Both Assertion and Reason are correct and Reason is the correct explanation for Assertion'.

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