Question

Assertion :RBC production is regulated by kidney. Reason: Erythropoietin reaches red bone marrow, induces stem cell mitosis and speeds up development of RBC.

• A. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
• B. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
• C. Assertion is correct but Reason is incorrect
• D. Both Assertion and Reason are incorrect

Answer 1

The correct option is A Both Assertion and Reason are correct and Reason is the correct explanation for Assertion

• The production of RBCs is regulated by a hormone called erythropoietin.
• Erythropoietin is produced in the kidney by peritubular cells that can detect tissue oxygen content. Red blood cells are formed in the red bone marrow of bones.
• Stem cells in the red bone marrow called hemocytoblasts to give rise to all of the formed elements in blood.
• If a hemocytoblast commits to becoming a cell called a proerythroblast, it will develop into a new red blood cell. Hence, RBC production is regulated by the kidney as Erythropoietin reaches red bone marrow, induces stem cell mitosis and speeds up development of RBC.

So, the correct answer is 'Both Assertion and Reason are correct and Reason is the correct explanation for Assertion'.