Assertion :Retroviruses or transposons can be used in the process of RNAi. Reason: RNAi takes place in all eukaryotic organisms as a method of cellular defense.
A
Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
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B
Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
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C
Assertion is correct but Reason is incorrect
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D
Both Assertion and Reason are incorrect
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Solution
The correct option is A Both Assertion and Reason are correct and Reason is the correct explanation for Assertion Both assertion and reasons are correct.
RNAi or RNA interference takes place in all eukaryotic cells as the cellular defense. This method involves silencing of a specific mRNA due to complementary double-stranded RNA molecule which binds and prevents translation of mRNA i.e. silencing. In case of viral infection, a retrovirus with RNA genome or mobile genetic element (transposons) can at as a complementary RNA molecule that replicates via an RNA intermediate.
RNAi has been used to target genes in several viral diseases such as HIV, and Hepatitis. HIV receptors are silenced to prevent entry of the virus into the host cell.